BioengineeringBioconjugate ChemistryPeer-reviewed
CD22L Conjugation to Insulin Attenuates Insulin-Specific B cell Activation
Kyle D. Apley, Amber Simone Griffith, Grant M. Downes…·Cory J. Berkland
This paper develops insulin-CD22L conjugates to inhibit anti-insulin B cells in T1D, finding that low-valency conjugates reduce B cell activation while high-valency ones promote it.
5 citations