Author

Grant M. Downes

University of KansasORCID 0000-0001-9063-7678Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Amber Simone GriffithiD· 1 shared Cory J. BerklandiD· 1 shared Kyle D. ApleyiD· 1 shared Mark P. FarrelliD· 1 shared Patrick A. RossiD· 1 shared Peggy L. KendalliD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperBioengineering

Amber Simone GriffithORCID

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1 paper

Recent·Most cited

BioengineeringBioconjugate ChemistryPeer-reviewedOct 26, 2023

CD22L Conjugation to Insulin Attenuates Insulin-Specific B cell Activation

Kyle D. Apley, Amber Simone Griffith, Grant M. Downes…·Cory J. Berkland

This paper develops insulin-CD22L conjugates to inhibit anti-insulin B cells in T1D, finding that low-valency conjugates reduce B cell activation while high-valency ones promote it.

5 citations

mouseproteomics

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