Kristine A. Kuhn

The paper identifies immune alterations preceding rheumatoid arthritis onset and provides tools for dataset exploration.

This study investigates the role of MAIT cells in a genetically diverse mouse model of spontaneous colitis, finding that MAIT cells drive chronic inflammation and colonic pathology.

The paper identifies shared transcriptional and cell communication signatures in RA patients and at-risk individuals, showing how multiple pathogenic mechanisms contribute to disease initiation and progression.

This study identifies green tea compounds in plasma of mice with and without gut microbiomes, showing their metabolism is influenced by microbiome composition and diversity.

This paper develops and tests two Nanoligomer-based therapies, CK1 and NI112, for IBD in mice, showing reduced disease severity and biomarker expression.

This study shows that microbiota-dependent indole production is essential for collagen-induced arthritis development and identifies potential therapeutic targets.

VOLARE is a web tool that visualizes microbiome-immune system relationships through interactive regression analysis, enabling domain experts to evaluate candidate results for further experimentation.