Josephine Louise Robb

This study shows that lipid droplet lipolysis in POMC neurons regulates energy homeostasis, with sex-specific effects on body weight and metabolism.

This study shows that inhibiting LSD1, a histone demethylase, restores learning and memory in aged mice by reversing age-related defects in H3K4me3 dynamics and synaptic plasticity.

This study shows DGAT1-dependent lipid droplet synthesis in microglia reduces pro-inflammatory cytokine production in response to LPS.

This study shows that systemic inflammation increases exploitative behavior in mice during patch-foraging tasks, suggesting a link between immunometabolic states and decision-making.

This study shows that inhibiting ATGL in microglia reduces LPS-induced inflammation and sickness behavior in mice.

This study investigates the role of TSPO in astrocyte metabolism and inflammation, finding that TSPO deficiency alters metabolic flexibility but not the inflammatory response to LPS.

This study shows that human astrocytes increase fatty acid oxidation under recurrent low glucose to maintain nucleotide levels, indicating mitochondrial dysfunction in hypoglycemia response.