Author

Yan Nie

University Health NetworkORCID 0000-0002-6956-0634Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Ailing Pon· 1 shared Andrew W. StamfordiD· 1 shared Anthony Joseph LambertoiD· 1 shared Anthony M. Barsotti· 1 shared Brian RaughtiD· 1 shared C.H. ArrowsmithiD· 1 shared Dalia Baršytė-LovejoyiD· 1 shared Derek J. WilsoniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Ailing Pon

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1 paper

Recent·Most cited

BiochemistryNature Chemical BiologyPeer-reviewedJul 4, 2024

Recruitment of FBXO22 for Targeted Degradation of NSD2

Yan Nie, John R. Tabor, Jianping Li…·C.H. Arrowsmith

This paper describes a targeted protein degradation strategy using UNC8732 to recruit FBXO22 for NSD2 degradation, leading to growth suppression and reversal of drug resistance in leukemia cells.

73 citationstop 1%

humanexperimental assay

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