Author

Sandra C. de Castro

University College LondonORCID 0000-0002-7002-015XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew J. CoppiD· 2 shared Chloe Santos· 2 shared Nicholas D. E. GreeneiD· 2 shared Abigail R. MarshalliD· 1 shared Ailish Murray· 1 shared Diana Gold Diaz· 1 shared Eirini ManiouiD· 1 shared Gabriel L. GaleaiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersDevelopmental Biology

Andrew J. CoppORCID

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2 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedDec 5, 2024

Spinal neural tube formation and tail development in human embryos

Chloe Santos, Abigail R. Marshall, Ailish Murray…·Andrew J. Copp

This study examines spinal neural tube formation and tail development in human embryos, finding patterns similar to mouse and rat, including primary neurulation completion and secondary neurulation characteristics.

13 citations

humanexperimental assay

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Molecular BiologyMolecular Genetics and MetabolismPeer-reviewedMay 15, 2024

AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia

Kit‐Yi Leung, Chloe Santos, Sandra C. de Castro…·Nicholas D. E. Greene

This study demonstrates that AAV-mediated GLDC expression reduces glycine levels and normalizes folate metabolism in a GLDC-deficient mouse model of NKH.

6 citations

mouseexperimental assay

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