NeuroscienceNeurobiology of DiseasePeer-reviewed
Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice
4 citations
Author
Carola A. Haas
University of FreiburgORCID 0000-0002-7022-4136Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2021-2025 · peak 4/yrCo-Author Collaboration Network
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Curved chords = mutual co-authorship10 papers
Recent·Most cited
- NeurosciencebioRxivPreprint
PEACOC - Detecting and classifying a wide range of epileptiform activity patterns in rodents
Katharina Heining, Antje Kilias, Philipp Janz…·Ulrich Egert
PEACOC detects and classifies diverse epileptiform activity patterns in rodents, revealing a continuum of spike loads and an anti-correlation with granule cell dispersion.
2 citations - NeurosciencebioRxivPreprint
Focal cortical dysplasia type II-dependent maladaptive myelination in the human frontal lobe
Catharina Donkels, Susanne Huber, Theo Demerath…·Carola A. Haas
This study examines myelination patterns in FCD IIa and IIb in the frontal lobe, finding divergent maladaptive myelination features between the two subtypes.
DOI 10.1101/2024.03.02.582894 - NeuroscienceBrain stimulationPeer-reviewed
Low frequency stimulation for seizure suppression: identification of optimal targets in the entorhinal-hippocampal circuit
Piret Kleis, Enya Paschen, Ute Häussler, Carola A. Haas
This study identifies presynaptic targets in the entorhinal-hippocampal circuit that effectively suppress seizures using low-frequency stimulation in a mouse model of MTLE.
4 citations - NeurosciencebioRxivPreprint
Probing hippocampal stimulation in experimental temporal lobe epilepsy with functional MRI
Niels Schwaderlapp, Enya Paschen, Pierre LeVan…·Carola A. Haas
This study investigates brain-wide responses to hippocampal electrical stimulation in a mouse model of mesial temporal lobe epilepsy using fMRI, finding that stimulation frequency, not amplitude, determines the extent of activation spread.
- NeuroscienceBrainPeer-reviewed
On-demand low-frequency stimulation for seizure control: efficacy and behavioral implications
Enya Paschen, Piret Kleis, Diego M. Vieira…·Carola A. Haas
This study evaluates on-demand low-frequency stimulation for seizure control in a mouse model of mesial temporal lobe epilepsy, showing improved efficacy and no cognitive deficits.
18 citations - NeuroscienceFrontiers in Cellular NeurosciencePeer-reviewed
Differential vulnerability of neuronal subpopulations of the subiculum in a mouse model for mesial temporal lobe epilepsy
Julia Franz, Nicole Barheier, Henrike Wilms…·Ute Häussler
The paper identifies cell loss and subtype-specific vulnerability of interneurons in the subiculum of a mouse model for mesial temporal lobe epilepsy.
12 citations - GeneticsNature GeneticsPeer-reviewed
Comprehensive multiomic profiling of somatic mutations in malformations of cortical development
Changuk Chung, Xiaoxu Yang, Taejeong Bae…·Eduardo Maury
This study identifies 69 mutated genes in malformations of cortical development using multiomic profiling of 317 brain resections and single-cell sequencing.
123 citationstop 1% - NeuroscienceBMC BiologyPeer-reviewed
In vivo characterization and application of a novel potassium channel-based optogenetic silencer in the healthy and epileptic mouse hippocampus
Piret Kleis, Enya Paschen, Ute Häussler…·Carola A. Haas
The paper develops and tests a novel optogenetic silencer, PACK, in healthy and epileptic mice, finding it effectively inhibits neuronal activity but causes side effects.
12 citations - NeuroscienceBiomaterialsPeer-reviewed
Transcriptional characterization of the glial response due to chronic neural implantation of flexible microprobes
Kevin Joseph, Matthias Kirsch, Midori Johnston…·Ulrich Hofmann
This study characterizes the transcriptional response of glial cells to chronic implantation of flexible microprobes over 18 weeks, showing initial activation and eventual partial normalization.
37 citations