Author

Sara Gago

University of ManchesterORCID 0000-0002-7027-4598Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andrew S. MacDonaldiD· 1 shared Catherine B. LawrenceiD· 1 shared Daniel P. ConniD· 1 shared Darren D. ThomsoniD· 1 shared David BroughiD· 1 shared Emer HickeyiD· 1 shared Emma L. HoulderiD· 1 shared Faten Al-Wathiqi· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperImmunology

Andrew S. MacDonaldORCID

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3 papers

Recent·Most cited

ImmunologyThe Journal of Cell BiologyPeer-reviewedMar 13, 2026

Cell volume tunes macrophage innate inflammatory responses through promoting type I interferon signalling.

James R. Cook, Tara A. Gleeson, Sara Gago…·J. P. Green

This study shows that cell volume changes in macrophages enhance type I interferon signaling and inflammation through a DNA- and STING-dependent mechanism.

2 citations

mousebulk RNA-seq

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GenomicsbioRxivPreprintFeb 17, 2025

Candida albicans genome adaptation in azole resistant isolates from autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) patients

Faten Al-Wathiqi, Sara Gago, Lilyann Novak Frazer…·Paul Bowyer

The paper analyzes genome sequences of Candida albicans isolates from APECED patients to identify genetic adaptations associated with azole resistance.

DOI 10.1101/2025.02.17.635002

C. eleganswhole-genome sequencing

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ImmunologyJournal of Allergy and Clinical ImmunologyPeer-reviewedNov 22, 2024

Aspergillus-mediated allergic airway inflammation is triggered by dendritic cell recognition of a defined spore morphotype, a process that can be targeted via antifungal therapeutics.

Emma L. Houlder, Sara Gago, George Vere…·Peter C. Cook

This study identifies a specific stage of Aspergillus fumigatus spore development that activates dendritic cells to trigger allergic airway inflammation and shows antifungal drugs can reduce this process.

9 citations

mouseexperimental assay

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