Hyun Hyung An

This study identifies an intronic SINE element that regulates Pou5f1/OCT4 repression in mouse trophectoderm, linking hormone signaling to blastocyst hatching and implantation.

This study shows that SMAD7 restrains TGFβ and BMP signaling to enable pre-HSC maturation into HSCs during embryonic hematopoiesis.

This study shows BMI1 promotes erythroid self-renewal through both gene repression and activation, offering a strategy to expand immature erythroid precursors for clinical use.

The paper identifies human erythroid progenitors as immune mediators expressing MHC class II machinery and interacting with T cells in the fetal liver.