Robert L. Fairchild

This study shows that NK cell activation via NKG2D and graft Rae-1e ligand is essential for antibody-mediated kidney allograft rejection, even with high DSA levels.

This study shows that NK cell allorecognition reprograms neutrophils in heart allografts, leading to a novel hybrid neutrophil subset that may impact transplant outcomes.

The paper shows that inhibiting de novo autoantibody production reduces chronic antibody-mediated rejection of kidney allografts, even when donor-specific antibody titers remain high.

The paper uses Digital Spatial Profiling to analyze transcript localization in renal transplant biopsies, showing compartmentalized immune responses and persistent podocyte transcript reduction during antibody-mediated rejection.