Author

Tiantai Ma

University of California San DiegoORCID 0000-0002-7150-7808Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:multiome· 1

Frequent Co-Authors

Jens Lykke‐AnderseniD· 3 shared Rea M. Lardelli· 2 shared Benjamin F. CravattiD· 1 shared Bingwen LuiD· 1 shared Bruno N. MelilloiD· 1 shared C Chaillan Huntington· 1 shared Daisuke OgasawaraiD· 1 shared David R. LiuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMolecular Biology

Jens Lykke‐AndersenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologybioRxivNov 21, 2025

Multiple Quality Control Checkpoints Safeguard Small Nuclear RNA Biogenesis and Prevent Assembly of Aberrant Spliceosomes

Tiantai Ma, C Chaillan Huntington, Zhuoyi Song…·Jens Lykke‐Andersen

The paper identifies quality control checkpoints in snRNA biogenesis that prevent defective snRNAs from forming aberrant spliceosomes and causing pre-mRNA splicing defects.

DOI 10.1101/gad.353690.126

humanmultiome

𝕏 PostBluesky

Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2024

The 3' exonuclease TOE1 selectively processes snRNAs through recognition of Sm complex assembly and 5' cap trimethylation

Tiantai Ma, Erica Xiong, Rea M. Lardelli, Jens Lykke‐Andersen

This study identifies how TOE1 selectively processes snRNAs by recognizing Sm complex assembly and 5' cap trimethylation, distinguishing them from other small non-coding RNAs.

13 citations

experimental assay

𝕏 PostBluesky

Systems BiologyNature Chemical BiologyPeer-reviewedOct 2, 2023

Assigning functionality to cysteines by base editing of cancer dependency genes

Haoxin Li, Tiantai Ma, Jarrett R. Remsberg…·Benjamin F. Cravatt

The paper uses base editing to assess the functional impact of cysteine mutations in cancer dependency genes, identifying essential and ligandable cysteines for drug development.

62 citationstop 2%

humanproteomics

𝕏 PostBluesky