Systems BiologybioRxivPreprint
Protection against APOE4-associated aging phenotypes with the longevity-promoting intervention 17α-estradiol in male mice
Cassandra Joan McGill, Amy Christensen, Wenjie Qian…·Christian J. Pike
This study shows that 17α-estradiol improves aging outcomes in APOE4 mice more than APOE3 mice, suggesting a genotype-dependent benefit of the intervention.
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