Mahmut Selman Sakar

This study shows that Pseudomonas aeruginosa becomes more tolerant to antibiotics when grown in confined spaces, due to mechanical stress-induced changes in efflux and membrane remodeling.

This study identifies species-specific oxygen sensing as a key factor in limb regeneration, showing that reducing oxygen sensing in amphibians enhances regenerative capacity while mammals require oxygen-sensitive pathways.

This study identifies POU5F1B as a human-specific oncoprotein that enhances cell invasiveness via plasma membrane remodeling through ubiquitination and S-acylation.

This paper develops microfabricated tools for long-term, minimally invasive imaging of the Drosophila ventral nerve cord in behaving adults, enabling longitudinal studies of neural circuit dynamics.