Gut archaea drive human MAIT cell responses
Natasha Fisher-Pearson, Martin Joseph Lett, Isaac W. D. Maylam…·Jethro S. Johnson
The paper shows that gut archaea produce 5-OP-RU, which activates MAIT cells, linking archaea to human immunity.
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University of BaselORCID 0000-0002-7230-9264Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Natasha Fisher-Pearson, Martin Joseph Lett, Isaac W. D. Maylam…·Jethro S. Johnson
The paper shows that gut archaea produce 5-OP-RU, which activates MAIT cells, linking archaea to human immunity.
Katia Sayaf, Martin Joseph Lett, Kate Powell…·Carl-Philipp Hackstein
This study identifies VEGFA, VEGFB, and vimentin as ligands expressed by MAIT cells that signal via VEGFR2 to promote tissue repair and liver regeneration.
Enja Tatjana Kipfer, David Hauser, Martin Joseph Lett…·Thomas Klimkait
The paper introduces a cloning-free reverse genetics platform for rapidly engineering SARS-CoV-2 variants and applies it to rescue Chikungunya and Dengue viruses.
Martin Joseph Lett, Fabian Otte, David Hauser…·Thomas Klimkait
This study develops a single-cycle SARS-CoV-2 vaccine that provides full protection and sterilizing immunity in hamsters against autologous challenge.