Simone Serio

The paper identifies a UHRF1-EM framework linking DNA methylation, developmental chromatin states, and prognosis in gastric, renal, and adrenal cancers, showing context-dependent prognostic associations.

This study identifies adventitial leptin receptor-expressing fibroblasts as key contributors to cardiac fibrosis after myocardial infarction in mice and humans.

This study shows RORγ mediates cancer-driven lipid dysmetabolism and myeloid immunosuppression by promoting MDSC expansion and M2 TAM polarization, with cholesterol lowering reversing these effects.

This study shows that ablating PALLD in adult hearts causes dilated cardiomyopathy with intercalated disc abnormalities and fibrosis, suggesting PALLD's essential role in cardiac function.