Drosophila midgut tumor-induced insulin resistance systemically remodels lymph gland hematopoiesis during cancer cachexia
Ujjayita Chowdhury, Gauri Panzade, Priya Neelesh Karnik…·Rohan Jayant Khadilkar
This study shows that tumor-induced insulin resistance in Drosophila remodels lymph gland hematopoiesis through ImpL2 overexpression and disrupts the Insulin-Wingless signaling axis.