Muscle spatial lipidomics identifies early ALS signatures in presymptomatic SOD1G93A mice
Mikel García-Puga, Cristina Huergo, Ainhoa Vidal-Gil…·Sonia Alonso‐Martín
The paper identifies early ALS-related lipid changes in presymptomatic SOD1G93A mice using lipid imaging mass spectrometry, showing sex-dependent and fiber-type-specific alterations detectable before symptoms.