Aaron Paul Russell

This study shows that stress reveals impaired endocrine coordination of glucose metabolism in dystrophin deficiency, with interventions improving glucose control and muscle function.

This paper develops and validates a SEC-SAX protocol for enriching extracellular vesicles from small plasma volumes for quantitative proteomics in human and mouse samples.

This study shows that TDP-43 aggregation in skeletal muscle causes motor dysfunction and neurodegeneration, but clearance of the protein allows for functional recovery.

This study shows that estrogen loss in female mdx mice reduces exercise capacity and mitochondrial metabolism, but estrogen replacement therapy can reverse these effects and upregulate Rbm20.

The paper isolates and analyzes the proteome of TDP-43-associated insoluble stress granules in an ALS mouse model, identifying sustained stress granule formation, CLUH granule recruitment, and impaired mitochondrial metabolism.