Jessica Wei

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

CINEMA-OT identifies causal effects of single-cell perturbations by separating confounding variation, outperforming existing methods on simulated and real datasets.

The paper identifies subtype-specific sublaminae in the ventral lateral geniculate nucleus (vLGN) that receive retinal input and are composed of distinct GABAergic neurons.