Yoshiaki Yasumizu

The paper benchmarks generative methods for designing peptides in TCR-pMHC complexes, revealing method-dependent differences in backbone generation and conformational diversity.

The paper identifies increased myeloid-driven inflammation in the CNS of prodromal Parkinson's Disease patients, linking gut and CNS immune responses through shared T cell clones.

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

This study uses spatial transcriptomics to identify medullary niche features in thymoma and thymic hyperplasia associated with myasthenia gravis pathogenesis.

VIRTUS detects and quantifies viral transcripts in RNA-seq data, enabling identification of infected cells and viral composition.