Giulia Bertolin

This study shows TERT interacts with TFAM to cause mitochondrial fragmentation and auto/mitophagy, affecting mitochondrial function and respiratory capacity.

The paper identifies mitochondrial inner membrane proteins interacting with AURKA and PHB2, showing their role in shaping metabolic heterogeneity and mitochondrial morphology in cancer cells.

The paper introduces BioSenSRRF, a method combining FRET biosensors with SRRF microscopy to study AURKA activation and mitochondrial activity at the nanoscale.

This study develops capsaicin-derived ligands that modulate the AURKA/PHB2 interaction and mitophagy in cancer cells, with compound 13 showing promise as a specific inhibitor of AURKA-dependent mitophagy.

This paper develops RalA-specific intrabodies that inhibit mitochondrial fission and extracellular vesicle secretion, reducing metastasis in a TNBC mouse model.

The paper investigates sex-specific mitochondrial membrane integrity differences in the auditory brainstem of a mouse model of Fragile X syndrome using fluorescence microscopy.

This study identifies Aurora-A as a splicing kinase that regulates alternative splicing by phosphorylating splicing factors and altering RNA motifs in affected regions.

The paper engineers a fluorescent chemogenetic reporter with tunable color for live-cell imaging, enabling advanced spectral control and compatibility with advanced imaging techniques.

The paper compares high-resolution image reconstruction methods for confocal microscopy, introducing a new deconvolution algorithm that improves resolution, contrast, and spatial intensity homogeneity.