Author

Jose Andres Alepuz Guillen

Boston UniversityORCID 0000-0002-7366-3484Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

David A. HarrisiD· 1 shared Janelle S. Vultaggio· 1 shared Jean R.P. GatdulaiD· 1 shared Robert C.C. MerceriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

David A. HarrisORCID

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1 paper

Recent·Most cited

NeurosciencePLoS PathogensPeer-reviewedJan 28, 2026

Membrane-anchored PrPSc is the trigger for prion synaptotoxicity

Jean R.P. Gatdula, Robert C.C. Mercer, Jose Andres Alepuz Guillen…·David A. Harris

This paper investigates the role of membrane-anchored PrPSc in prion-induced synaptotoxicity and shows that preventing its formation reduces synaptic damage.

6 citationstop 2%

mouseexperimental assay

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