Ryan P. Schreiner

This study shows that reducing sAC activity restores pigmentation in OCA models and increases melanin synthesis, suggesting targeting melanosome pH as a therapeutic strategy for OCA and skin cancer risk.

This study shows that SPRY4-ERK signaling acts as a checkpoint to restore spermatogenesis after germline stem cell damage, with its loss leading to impaired regeneration and fertility.

This study develops an in vitro method to generate human intestinal organoids containing multiple cell types, including neurons, endothelial cells, and smooth muscle, which functionally mimic gut physiology.

This paper introduces a method to identify miRNA targets in vivo using Halo-Enhanced Ago2 Pulldown and demonstrates its application in mouse models.