Shane C. Wright

This study shows that reduced NR4A3 levels in skeletal muscle due to inactivity impair glucose metabolism, translation, and myotube size by affecting mTORC1 and ribosomal pathways.

This study identifies and characterizes synthetic ligands for HCAR1 using ebBRET, revealing its activation of Gi/o and Gs pathways without β-arrestin recruitment.

This study identifies virapinib, a novel inhibitor of macropinocytosis that blocks viral entry by SARS-CoV-2, Monkeypox virus, and TBEV without host cell toxicity.