Chase J. Morgan

This study identifies Rhc as a multifunctional protein essential for DNA replication and transcription in nucleus-forming phages, revealing its role in resolving R-loops and coordinating gene expression.

The paper shows that Chimalliviridae form a lipid membrane-bound EPI vesicle during early infection, which hosts transcription of the phage genome, and demonstrates the necessity of a second compartment, the phage nucleus, for genome replication.

The paper identifies gp335, a phage protein from Churi, which inhibits Pseudomonas aeruginosa growth by interfering with protein translation through ribosome association.

The paper shows a mobile intron in bacteriophage ΦPA3 uses its homing endonuclease to interfere with co-infecting phage ΦKZ, providing a competitive reproductive advantage.

This paper identifies components of a novel protein import pathway in phages, revealing a mechanism for selective protein trafficking into the phage nucleus.