Chromatin signalling pathways and FANCE amplification affect ATR inhibitor sensitivity in metastatic breast cancer
Jogitha Selvarajah, Rayzel Candida Fernandes, Marc P. Lorentzen…·Charlotte Lynne Bevan
Author
Imperial College LondonORCID 0000-0002-7533-0552Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jogitha Selvarajah, Rayzel Candida Fernandes, Marc P. Lorentzen…·Charlotte Lynne Bevan
Dimitrios Doultsinos, Ingrid Tomljanović, Eleftherios D. Pilalis…·Ian Geoffrey Mills
This paper identifies IRE1 activity as a regulator of prostate cancer cell lineage states and shows its role in predicting prognosis and treatment response across localized and metastatic disease.
Oluwadamilola D. Ogunjinmi, Tukur Abdullahi, Riaz‐Ali Somji…·Efstathios S. Giotis
This study investigates enzalutamide's antiviral effects against seasonal coronaviruses and identifies differences in viral-androgen signaling interactions between HCoV-229E and HCoV-OC43.
Theodora A. Constantin, Anabel Varela‐Carver, Kyle K. Greenland…·Charlotte Lynne Bevan
This study investigates the antitumour activity of CT7001, a CDK7 inhibitor, in castration-resistant prostate cancer models, showing it inhibits proliferation and enhances enzalutamide efficacy.