Author

Johann Biedermann

Leibniz-Forschungsinstitut für Molekulare PharmakologieORCID 0000-0002-7542-1999Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Assay:electrophysiology· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Han SuniD· 3 shared Andrew J.R. PlestediD· 1 shared Berke TürkaydiniD· 1 shared Ece Kuru· 1 shared Elena B. RieliD· 1 shared Florian HeiseriD· 1 shared Friederike SchulziD· 1 shared Haoran LiuiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

Han SunORCID

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3 papers

Recent·Most cited

BiophysicsCommunications BiologyPeer-reviewedAug 23, 2025

Atomistic Mechanism of Cation Permeation and Pore Voltage Sensitivity in Cyclic Nucleotide-Gated CNGA1 Ion Channel

Haoran Liu, Johann Biedermann, Han Sun

The paper uses molecular dynamics simulations to reveal the atomistic mechanism of cation permeation and voltage sensitivity in the CNGA1 ion channel.

3 citations

mechanistic / dynamical modelprotein folding & dynamics

𝕏 PostBluesky

BiophysicsProceedings of the National Academy of SciencesPeer-reviewedAug 14, 2025

Atomistic Mechanisms of Calcium Permeation Modulated by Q/R Editing and Selectivity Filter Mutations in GluA2 AMPA Receptors

Florian Heiser, Johann Biedermann, Ece Kuru…·Han Sun

This study investigates the atomistic mechanisms of calcium permeation in GluA2 AMPA receptors, showing how Q/R editing and selectivity filter mutations modulate ion selectivity and conductance.

4 citations

humanelectrophysiology

𝕏 PostBluesky

BiophysicsNature CommunicationsPeer-reviewedMay 31, 2024

From head to tail - Atomistic mechanism of long-range coupling from the cytosolic sensor domain to the selectivity filter in TREK K2P channels

Berke Türkaydin, Marcus Schewe, Elena B. Riel…·Han Sun

The paper reveals the atomistic mechanism of long-range coupling between the cytosolic sensor domain and the selectivity filter in TREK K2P channels, showing how conformational changes and phosphorylation regulate channel activity.

24 citations

structural biologybiophysical modeling

𝕏 PostBluesky