Pavel Abaffy

This study uses synthetic modified mRNAs to stimulate beta-cell proliferation in rodents and humans, showing temporary activation of cell cycle pathways without sustained proliferation.

The paper uses snRNA-seq to study B chromosome elimination in sorghum embryos, identifying two subpopulations of B-containing nuclei with distinct transcriptional profiles.

The paper introduces a method to profile microglia from frozen brain tissue using PU.1 as a marker and Smart-seq3xpress, showing improved transcriptomic data compared to standard protocols.

This study maps the spatiotemporal transcriptomic changes in mouse brain tissue after ischemic injury, revealing glial cell responses and their role in neuroinflammation.

This study identifies Regeneration Initiating Cells (RICs) in Xenopus laevis tail regeneration using single cell and spatial transcriptomics, showing their role in initiating regeneration by modifying the extracellular matrix.

The paper uses TOMO-Seq to compare maternal RNA localization across four fish and amphibian species, revealing diverse localization patterns and poor correlation between vegetally localized genes.

The paper analyzes RNA-Seq data from young and aged mice after ischemic stroke to identify age-related transcriptional changes and inflammatory responses.