Synthetic BiologybioRxivPreprint
EnzymeCAGE: A Geometric Foundation Model for Enzyme Retrieval with Evolutionary Insights
Yong Liu, Chenqing Hua, Tao Zeng…·Shuangjia Zheng
EnzymeCAGE is a geometric foundation model trained on enzyme-reaction pairs to predict enzyme function, de-orphan reactions, identify catalytic sites, and reconstruct biosynthetic pathways.