Quan Xu

The paper introduces a platform for high-throughput spatial phenotyping of multilineage organoids, identifying pathway modulators and treatment strategies for PDAC.

The paper integrates single-cell transcriptomes and spatial transcriptomics to identify therapeutic targets in pancreatic cancer by analyzing cell states and ligand-receptor interactions in tumoroids.

This paper creates a human endoderm organoid cell atlas by integrating single-cell transcriptomes from multiple organoid types to compare cell states with primary tissues and disease models.

OncoPubMiner is a platform that mines oncology publications to create structured knowledge bases, enabling efficient and accurate gathering of precision oncology insights from scientific articles.

ANANSE predicts key transcription factors in cell fate determination by analyzing enhancer-based regulatory networks across 18 human tissues.

The paper uses single-cell RNA-seq to identify a reversible epithelial-mesenchymal transition in p63 mutation-induced differentiation defects of human iPSCs.