Valentin J. Maurer

This study introduces scIRES-seq to analyze CTCs from cervical cancer, revealing multimodal molecular heterogeneity through integrated genetic, epigenomic, and transcriptomic profiling.

This study identifies oncofetal reprogramming in juvenile myelomonocytic leukemia, linking RAS-pathway activation to fetal gene expression and revealing CD52 as a therapeutic target.

This paper introduces rejection sampling to improve macromolecular complex detection in cryo-electron tomography by incorporating biological constraints, achieving performance comparable to deep learning methods without annotated data.

The paper introduces HMFF, a method integrating experimental data into membrane simulations, and applies it to various biological systems to enable multi-scale modeling.

AlphaPulldown2 provides a pipeline for high-throughput protein structural modeling with automated workflows and improved data management.

ColabSeg is a tool for processing and visualizing membrane segmentations from cryo-ET data, enabling high-throughput segmentation and training of CNNs.

The paper introduces pyTME, a Python library for template matching in cryo-EM data that improves efficiency and scalability for large datasets.

This paper introduces a reference-free deconvolution protocol for DNA methylomes to identify hidden cell populations in complex samples, applied to lung cancer data from TCGA.