Nathalie Mougenot

This study shows maternal obesity accelerates cardiomyocyte maturation in offspring, leading to adult heart dysfunction through cytoarchitectural disruption.

This study identifies Loxl2 as a therapeutic target for LMNA cardiomyopathy by showing its role in ECM remodeling in patient-derived cardiomyocytes and mouse models.

This paper demonstrates that overexpressing the N-terminal fragment of Nav1.5 restores cardiac sodium current and electrical activity in models of Brugada syndrome.

This study shows that CASK depletion improves intercalated disc organization and ventricular function in multiple models, suggesting CASK as a repressor of ID structure and function in cardiac disease.

The paper identifies a subset of epicardial-derived cells that contribute to fibro-fatty infiltration in diseased atria through single-cell RNA-seq and lineage tracing.