Masami Kanai‐Azuma

This study shows that ectopic SOX17 in Sertoli cells promotes Sertoli valve formation and partially rescues infertility in Sox17-null mice.

This study shows that knocking out Rtl8a and Rtl8b in mice leads to reduced social behavior, increased apathy, and obesity, likely due to decreased GABRB2 expression in the brain.

This study shows that Rtl8a and Rtl8b double knockout mice develop late-onset obesity and neurodevelopmental defects, indicating these retrovirus-derived genes are important for brain function.

This study identifies Rasip1 as a downstream target of Sox17 that enhances hematopoietic activity in intra-aortic hematopoietic clusters of midgestation mouse embryos.

This study shows that Wnt signaling in pre-granulosa cells is essential for follicle activation and oocyte maturation, with a two-step model involving self-activation of Wnt and subsequent support of oocyte reawakening.

This study shows that Sox17 expression in cardiac progenitor cells biases their fate toward the endocardium and regulates myocardium development through NOTCH signaling in mice.

This paper shows that Nr5a1 suppression during fetal development optimizes ovarian development by fine-tuning Notch signaling, using mouse models with altered Nr5a1 expression.