Author

Nannan Li

Abramson Cancer CenterORCID 0000-0002-7786-892XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Donald M. O’RourkeiD· 2 shared Meghan T. LoguniD· 2 shared Zev A. BinderiD· 2 shared Arati Suvas DesaiiD· 1 shared Bike Su OneriD· 1 shared Chuncheng XieiD· 1 shared Daniel Y. Zhang· 1 shared Don L. SiegeliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Donald M. O’RourkeORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologyCell stem cellPeer-reviewedDec 9, 2024

Patient-derived glioblastoma organoids as real-time avatars for assessing responses to clinical CAR-T cell therapy

Meghan T. Logun, Xin Wang, Yusha Y. Sun…·Donald M. O’Rourke

The paper shows that patient-derived glioblastoma organoids can reflect CAR-T cell treatment responses in real-time, correlating with clinical outcomes in patients.

126 citationstop 1%

humanorganoid / primary culture

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Cancer BiologyMolecular TherapyPeer-reviewedJul 30, 2024

Armored Bicistronic CAR T Cells with Dominant-negative TGF-β Receptor II to Overcome Resistance in Glioblastoma.

Nannan Li, Jesse L. Rodriguez, Yibo Yin…·Donald M. O’Rourke

This paper develops a tri-modular CAR T cell construct with a dominant-negative TGF-β receptor II to overcome GBM resistance by enhancing T cell function and efficacy in a preclinical model.

81 citationstop 1%

mouseexperimental assay

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