Synthetic BiologyMetabolic Engineering CommunicationsPeer-reviewed
Improved protein glycosylation enabled heterologous biosynthesis of monoterpenoid indole alkaloids and their unnatural derivatives in yeast
Mohammadamin Shahsavarani, Joseph Christian Utomo, Rahul Kumar…·Yang Qu
This study improves yeast-based biosynthesis of monoterpenoid indole alkaloids by expressing a key enzyme and integrating biosynthetic gene cassettes, enabling production of vinblastine precursors and their unnatural derivatives.
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