BiochemistryJournal of Biological ChemistryPeer-reviewed
Development of LRRK2 designed ankyrin-repeat proteins
Verena Dederer, Marta M. Sanz Murillo, Eva Pauline Karasmanis…·Stefan Knapp
This study develops a high-affinity DARPin that binds to LRRK2's WD40 domain, improving structural analysis and revealing its role in disrupting LRRK2 filaments and Rab8A phosphorylation.
11 citations