Author

Valerie J. Rodriguez-Irizarry

The University of Texas Southwestern Medical CenterORCID 0000-0002-7914-0684Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Julie K. PfeifferiD· 2 shared Robert W. MaplesiD· 2 shared Melissa R. BudiciniiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersMicrobiology

Julie K. PfeifferORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS BiologyPeer-reviewedJun 24, 2025

Egress-enhancing mutation reveals inefficiency of non-enveloped virus cell exit

Valerie J. Rodriguez-Irizarry, Robert W. Maples, Julie K. Pfeiffer

The paper identifies an egress-enhancing mutation in murine norovirus that increases replication speed and viral titers in mice.

1 citation

mouseexperimental assay

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MicrobiologyJournal of VirologyPeer-reviewedApr 23, 2024

Murine norovirus mutants adapted to replicate in human cells reveal a post-entry restriction

Melissa R. Budicini, Valerie J. Rodriguez-Irizarry, Robert W. Maples, Julie K. Pfeiffer

This study identifies mutations in murine norovirus that enhance replication in human cells, revealing post-entry restrictions in addition to receptor expression.

10 citations

mousebulk RNA-seq

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