Author

Mark Castleberry

Vanderbilt University Medical CenterORCID 0000-0002-7916-5451Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Danielle L. MichelliD· 3 shared Kasey C. VickersiD· 3 shared Clark MassickiD· 2 shared Elizabeth M. SemleriD· 2 shared J. Jeffrey CarriD· 2 shared MacRae F. LintoniD· 2 shared Marisol Adelina RamireziD· 2 shared Quanhu ShengiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Danielle L. MichellORCID

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3 papers

Recent·Most cited

Cell BiologyAtherosclerosisPeer-reviewedNov 20, 2025

Post-transcriptional modifications on tRNA fragments confer functional changes to high-density lipoproteins in atherosclerosis

Elizabeth M. Semler, Danielle L. Michell, Philip J. Kingsley…·Kasey C. Vickers

The paper investigates how post-transcriptional modifications on tRNA fragments in HDL affect atherosclerosis by altering immune signaling and macrophage activation.

2 citations

humanbulk RNA-seq

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BioengineeringNucleic Acids ResearchPeer-reviewedJun 20, 2025

Lipid-siRNA conjugate accesses a perivascular transport mechanism and achieves widespread and durable knockdown in the central nervous system

Alexander G. Sorets, Katrina R Schwensen, Nora Francini…·Ethan S. Lippmann

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

11 citations

mousescRNA-seq

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Molecular BiologyJournal of Biological ChemistryPeer-reviewedApr 18, 2022

Physico-chemical principles of HDL-small RNA binding interactions.

Danielle L. Michell, Ryan M. Allen, Ashley B. Cavnar…·Kasey C. Vickers

The paper investigates how HDL binds to single-stranded small RNAs through interactions with apoA-I, revealing mechanisms that may enable extracellular RNA communication.

8 citations

humanexperimental assay

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