Kasey C. Vickers

This study shows that N-aldehyde modified phosphatidylethanolamines (NAMPs) inhibit efferocytosis and are elevated under oxidative stress conditions.

The paper investigates how post-transcriptional modifications on tRNA fragments in HDL affect atherosclerosis by altering immune signaling and macrophage activation.

This study develops a lipid-siRNA conjugate that uses perivascular transport to achieve long-lasting gene knockdown in the CNS without toxicity.

This study identifies miR-100 and miR-125b as regulators of 3D growth and invasiveness in cancer cells, showing they can be transferred extracellularly to silence target genes in recipient cells.

This study shows that 5-FU treatment alters the export and base modifications of small RNAs in extracellular vesicles from colorectal cancer cells.

The paper identifies miRNA expression changes in neonatal patients during and after cardiopulmonary bypass, linking them to inflammation and signal transduction pathways.

The paper investigates how HDL binds to single-stranded small RNAs through interactions with apoA-I, revealing mechanisms that may enable extracellular RNA communication.

This study shows that inhibiting miR-22-3p reduces lymphocyte accumulation and kidney disease in a mouse model of systemic lupus erythematosus.

The paper introduces TIGER, a pipeline for analyzing extracellular small RNAs, demonstrating its ability to identify sRNAs on lipoproteins and in biofluids with high accuracy.