Author

Kiera L. Malone

University of VermontORCID 0000-0002-7943-4359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

Karen C. GlassiD· 2 shared Michael A. CianfroccoiD· 2 shared Ajit SinghiD· 1 shared Eugene Y. D. ChuaiD· 1 shared Hassan ZafariD· 1 shared James M. Lignos· 1 shared Jill E. MacfarlaneiD· 1 shared Kathleen M. TrybusiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 26 mutual co-author links

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2 shared papersBiochemistry

Karen C. GlassORCID

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2 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 3, 2026

Cryo-EM Structure of Human ATAD2B Reveals a Hexameric Organization Contributes to ATPase Activity and Substrate Coordination

Kiera L. Malone, Eugene Y. D. Chua, James M. Lignos…·Karen C. Glass

This study presents the cryo-EM structure of human ATAD2B, revealing its hexameric organization and providing insights into its ATPase activity and substrate coordination.

DOI 10.64898/2026.04.02.716110

humancryo-EM

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BiochemistryActa Crystallographica Section D Structural BiologyPeer-reviewedFeb 5, 2026

Breaking Barriers: Transitioning from X-ray Crystallography to Cryo-EM for Structural Studies

Hassan Zafar, Kiera L. Malone, Ajit Singh…·Karen C. Glass

This paper describes a laboratory's transition from X-ray crystallography to cryo-EM for studying ATAD2B, detailing challenges and strategies in sample preparation, data processing, and model building.

2 citations

cryo-EMmicroscopy & imaging analysis

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