Yeh‐Hsing Lao

Squidiff predicts transcriptomic changes across cell types in response to environmental stimuli using a diffusion model, enabling in silico screening for drug discovery and precision medicine.

This paper creates a vascular organoid model with an AKT1 mutation to study Proteus syndrome and finds AKT inhibitors reverse vascular malformations.

Starfysh integrates spatial transcriptomics and histology to analyze tumor microenvironments, identifying disease-specific spatial hubs and immune interactions in breast cancers.