Gordana Vunjak‐Novakovic

This study uses stiffening hydrogels to model fibrosis stages and shows how different stiffness levels affect fibroblast activation and cytokine secretion.

Squidiff predicts transcriptomic changes across cell types in response to environmental stimuli using a diffusion model, enabling in silico screening for drug discovery and precision medicine.

This study uses mechanical oscillation to enhance endosomal escape of mRNA delivered by lipid nanoparticles, improving transfection efficiency without harming cell viability or organelle integrity.

This study uses engineered human cardiac tissues to show how SLE autoantibodies affect myocardial injury through distinct binding patterns and functional effects on cardiac cells.

This paper creates a vascular organoid model with an AKT1 mutation to study Proteus syndrome and finds AKT inhibitors reverse vascular malformations.

This study demonstrates that human pluripotent stem cell-derived progenitors can engraft in rat lungs and promote injury repair while preventing conditioning-induced damage.

This study identifies LINC00881 as a key regulator of calcium handling in failing human hearts through DNA methylation analysis and functional studies in iPSC-derived cardiomyocytes.