Kerwyn Casey Huang

This study uses single-cell RNA-sequencing to analyze cell type-specific responses to young or aged blood in heterochronic parabiosis, identifying mitochondrial function as a key factor in rejuvenation.

This paper introduces a method to extract the phylogenetic dimension of coevolution, revealing hidden functional signals in proteins and improving structural-contact prediction.

This paper develops a fast, cheap protocol for assembling ordered transposon insertion libraries in anaerobic bacteria, using cell sorting and barcoded transposons to improve accuracy and efficiency.

The paper uses chemical-genetic analysis of RNA polymerase mutants to uncover structure-function relationships and physiological trade-offs in Escherichia coli.

The paper identifies YhdP as a modulator of phospholipid transport rate in Escherichia coli, showing its role in controlling inner membrane shrinkage and outer membrane rupture during mlaA* mutation.

The paper develops a general model to explore how cell-cycle regulation mechanisms are constrained by cell-size homeostasis measurements across different organisms.

Bellymount allows long-term, non-invasive imaging of Drosophila abdominal organs and gut microbiota, enabling tracking of cellular and microbial dynamics over multiple days.