Akos A. Gerencser

The paper introduces PickliPy, an open-source framework for converting assay designs into ADE picklists, enabling reproducible and scalable microplate-based experiments.

This study identifies functionally distinct senescent cell subpopulations based on cell cycle status, showing G2-arrested cells secrete more IL-6 and are more sensitive to senolytic treatment.

The paper introduces FAST, an automated method for high-throughput senescence quantification using image-based markers, showing it accurately measures senescence burden across cell types and reduces false positives.

The paper performs proteomic analysis of Huntington's disease patient-derived medium spiny neurons, identifying altered lipid metabolism and lipid droplet accumulation as key findings.