Grigorii Nos

This study shows that Ag-Neo2/15 scaffolds expand antigen-specific T cells with enhanced cytotoxicity and reduced dysfunctionality compared to Ag-IL2/21 scaffolds.

This study identifies impaired HPV-specific CD8 T cell recognition and a suppressive immune microenvironment in cervical cancer, highlighting the need for enhanced T cell responses and immune suppression targeting.

ITRAP2 improves TCR-pMHC pairing accuracy by reducing noise and cross-contamination in single-cell data, outperforming existing methods on both in-house and public datasets.

The paper identifies a concise set of 137 virus-specific CD8 T cell epitopes recognized by human T cells, with 84% showing prevalent reactivity and associations with effector and memory phenotypes.