Hod Dana

This study shows that preventing microglial reactivity protects against acute and progressive neurological dysfunction and motor impairments caused by alcohol abuse in mice.

This study shows that remyelinating therapy with clemastine restores neuronal activity in a mouse model of demyelination, with sex-dependent recovery patterns.

This study shows that systemic exposure to SARS-CoV-2 virus-like particles disrupts cortical neuronal activity in mice, with persistent effects and heightened vulnerability in htau mice.

This study develops an in vivo method to monitor axonal activity over time in mice and shows that P7C3-A20 reduces but does not eliminate axonal dysfunction after brain injury.

This paper introduces a method to record single-cell cortical activity from freely-moving mice using CaMPARI, revealing task-dependent activity patterns in motor and somatosensory cortices.

This study uses two-photon microscopy to monitor functional changes in rat cortical regions after ischemic stroke, revealing widespread neuronal activity modifications across multiple brain areas.

The paper monitors hippocampal neuronal activity during demyelination and remyelination in mice, finding reduced firing rates during demyelination and partial recovery after remyelination.

The paper presents transgenic mice expressing the red calcium indicator jRGECO1a for in vivo neuronal imaging, showing comparable or better signal-to-noise ratios than viral methods.

Structure-guided mutagenesis of GCaMP6 plus neuron-based screening yields a jGCaMP7 family, each variant tuned to a different regime: single spikes, neurites and neuropil, or population imaging.

The paper introduces improved red calcium indicators that match the sensitivity of GFP-based indicators, enabling better in vivo neural activity imaging.