Author

Zhentai Huang

University of PittsburghORCID 0000-0002-8102-464XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Aidan R. ColeiD· 2 shared Amandine AmalriciD· 2 shared Apoorva UbovejaiD· 2 shared Baixue YangiD· 2 shared Katherine M. AirdiD· 2 shared Nadine HempeliD· 2 shared Nathaniel W. SnyderiD· 2 shared Naveen Kumar TanguduiD· 2 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Aidan R. ColeORCID

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2 papers

Recent·Most cited

Cancer BiologyNaturePeer-reviewedMay 27, 2026

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

Apoorva Uboveja, Baixue Yang, Raquel Buj…·Katherine M. Aird

This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.

10 citations

humanproteomics

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Cell BiologyEMBO ReportsPeer-reviewedJun 13, 2025

ATR promotes mTORC1 activity via de novo cholesterol synthesis

Naveen Kumar Tangudu, Alexandra N. Grumet, Richard S. Fang…·Katherine M. Aird

This study shows ATR enhances mTORC1 activity through cholesterol synthesis via LSS, independent of CHK1 and TSC, and this effect is amplified in p16-deficient cells.

6 citations

humanexperimental assay

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