Andrew A. Bridges

The paper introduces PULLI, a computer vision platform that extracts phenotypes from bacterial growth timelapses, revealing genotype-phenotype relationships in Vibrio cholerae mutants.

This study introduces LFAB, a label-free microscopy method for high-throughput biofilm analysis, and identifies key genes regulating biofilm formation in Streptococcus pneumoniae.

The paper shows that during biofilm dispersal, a subpopulation of cells forms a resilient post-dispersal biofilm community that can re-populate the niche and resist antibiotics and bacteriophages.

This study identifies DbfQ as a periplasmic protein that modulates the DbfRS two-component system in Vibrio cholerae, affecting biofilm dispersal and transcriptional responses to environmental stress.

This study uses far-red fluorogenic probes to reveal single-cell dispersal patterns in Vibrio cholerae biofilms, showing that dispersal starts at the periphery and 25% of cells never disperse.

This paper shows pneumococcal extracellular vesicles carry DNA that can be transferred to competent cells via the transformation machinery, promoting horizontal gene transfer and potential antibiotic resistance spread.

This paper uses video analysis to predict bacterial genotypes from spatiotemporal growth patterns, showing that low-resolution microscopy videos can classify genetic modifications in Vibrio cholerae.