ImmunologybioRxivPreprint
Antigen-specific Th17 T cells offset the age-related decline in durable T cell immunity
Ines Sturmlechner, Abhinav K. Jain, Jingjing Jiang…·Jörg J. Goronzy
Aging primarily impairs the CD8+ T cell VZV vaccine response, while effective VZV vaccination in older adults induces antigen-specific Th17 CD4+ T cells to compensate for aging defects.
DOI 10.1101/2025.06.05.658069