Author

Leendert H. J. Looijenga

Princess Máxima CenterORCID 0000-0002-8146-1911Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:mouse· 1

Frequent Co-Authors

Thomas F. EleveldiD· 2 shared A. J. M. Gillis· 1 shared Ad J. M. Gillis· 1 shared Ad J.M. Gillis· 1 shared Amanda R. LoehriD· 1 shared Amy L. HardingiD· 1 shared Andrew David MilleriD· 1 shared Bethany M. JamesiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

Thomas F. EleveldORCID

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3 papers

Recent·Most cited

Cancer BiologyCommunications MedicinePeer-reviewedApr 17, 2026

Identification and validation of liquid biopsy-based methylation biomarkers: a germ cell tumor subtype-specific study

Ferdinand W. Janssen, Ad J.M. Gillis, Puck B. Gouswaart…·Leendert H. J. Looijenga

This study identifies and validates methylation biomarkers for YST subtype-specific liquid biopsy in germ cell tumors using DNA methylation data and qPCR validation.

2 citationstop 2%

humanDNA methylation

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Cancer BiologyScientific ReportsPeer-reviewedFeb 5, 2025

Analysis of a mouse germ cell tumor model establishes pluripotency-associated miRNAs as conserved serum biomarkers for germ cell cancer detection

Amanda R. Loehr, Dennis M. Timmerman, Michelle Liu…·Robert S. Weiss

This study identifies miR-290-295 and miR-371-373 clusters as conserved serum biomarkers for detecting germ cell tumors in mice and humans.

5 citations

mousebulk RNA-seq

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Cell BiologybioRxivPreprintSep 21, 2023

Cytogenetic resource enables mechanistic resolution of changing trends in human pluripotent stem cell aberrations linked to feeder-free culture

Dylan Stavish, Christopher J. Price, Gabriele Gelezauskaite…·Ivana Barbaric

The paper analyzes genetic changes in human pluripotent stem cells under different culture conditions and identifies a link between feeder-free culture and increased chromosome 1q gains.

8 citations

humanDNA methylation

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